Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19890880 | 1.00 | LMNA (0.50) | LMNATSHRNPSR1GAAALDH1A1 | |
| SCHEMBL24088583 | 1.00 | LMNA (0.50) | LMNATSHRNPSR1GAAALDH1A1 | |
| SCHEMBL20079129 | 0.82 | TSHR (0.32) | LMNATSHRNPSR1GAATDP1 | |
| SCHEMBL23793795 | 0.82 | TSHR (0.32) | LMNATSHRNPSR1GAATDP1 | |
| SCHEMBL24998592 | 0.81 | LMNA (0.47) | LMNATSHRNPSR1GAAALDH1A1 | |
| SCHEMBL20079069 | 0.80 | ALDH1A1 (0.31) | LMNATSHRNPSR1GAAALDH1A1 | |
| SCHEMBL23940856 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL25615831 | 0.76 | TDP1 (0.42) | LMNATSHRALDH1A1TDP1MAPT | |
| SCHEMBL20430613 | 0.76 | LMNA (0.58) | LMNATSHRNPSR1GAAALDH1A1 | |
| SCHEMBL21695108 | 0.75 | LMNA (0.42) | LMNATSHRNPSR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668860-B1 | CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |