Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191755 | 0.75 | MAPT (0.69) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL19477810 | 0.74 | MAPK10 (0.53) | MAPTALDH1A1RAB9AGAAMAPK10 | |
| SCHEMBL23794890 | 0.74 | GAA (0.46) | MAPTALDH1A1NPC1GAASMN1; SMN2 | |
| SCHEMBL5923798 | 0.73 | MAPT (0.67) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL7982480 | 0.72 | MAPK10 (0.69) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL29740043 | 0.72 | MAPT (0.65) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL1518631 | 0.72 | MAPK10 (1.00) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL9820213 | 0.71 | MAPT (0.64) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL23794889 | 0.71 | MEN1 (0.64) | MAPTNPC1RAB9AEGFRSMN1; SMN2 | |
| SCHEMBL11813903 | 0.71 | MAPT (0.83) | MAPTALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |