Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794896 | 0.80 | RAB9A (0.59) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL1085867 | 0.77 | MEN1 (0.71) | MEN1KMT2AMAPTMAPK1EGFR | |
| SCHEMBL73115 | 0.76 | BACE1 (0.45) | MEN1KMT2AEGFRABCG2ABCB1 | |
| SCHEMBL13302353 | 0.75 | MEN1 (0.69) | MEN1KMT2AMAPTMAPK1EGFR | |
| SCHEMBL21258948 | 0.74 | MEN1 (0.67) | MEN1KMT2AMAPTMAPK1EGFR | |
| SCHEMBL1921496 | 0.74 | MTNR1B (0.72) | MEN1KMT2AMAPTMAPK1EGFR | |
| SCHEMBL5765529 | 0.74 | KMT2A (0.50) | MEN1KMT2AMAPTMAPK1ROCK1 | |
| SCHEMBL26186649 | 0.74 | EGFR (0.59) | MEN1KMT2AMAPTMAPK1EGFR | |
| SCHEMBL7968715 | 0.73 | MEN1 (0.66) | MEN1KMT2AMAPTMAPK1EGFR | |
| SCHEMBL1377802 | 0.73 | EGFR (1.00) | MEN1KMT2AMAPTMAPK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |