Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463913 | 0.78 | MAPK10 (0.53) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL19477810 | 0.78 | MAPK10 (0.53) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL23794886 | 0.74 | MAPT (0.62) | GAAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5765529 | 0.72 | KMT2A (0.50) | GAASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL304891 | 0.72 | CXCR2 (0.54) | GAAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22529449 | 0.71 | MAPK1 (0.54) | GAAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29463935 | 0.71 | MAPK1 (0.54) | GAAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1920752 | 0.70 | CXCR2 (0.52) | GAAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2485883 | 0.69 | KMT2A (0.73) | GAAPOLBMAPK8SMN1; SMN2MEN1 | |
| SCHEMBL23794894 | 0.69 | AURKA (0.49) | GAAPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |