Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760468 | 0.88 | CYP2D6 (0.64) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL14535338 | 0.88 | CYP2D6 (0.64) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL13283984 | 0.86 | KDM4E (0.65) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL30097942 | 0.86 | KDM4E (0.65) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL30225036 | 0.86 | KDM4E (0.65) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL8328390 | 0.86 | KDM4E (0.65) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL15278795 | 0.86 | KDM4E (0.65) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL2760465 | 0.86 | KDM4E (0.65) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A | |
| SCHEMBL12870505 | 0.84 | CYP2D6 (0.45) | CYP2D6KDM4EALDH1A1CYP3A4NPSR1 | |
| SCHEMBL522674 | 0.77 | CYP2D6 (0.63) | CYP2D6KDM4EALDH1A1HSD17B10ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287032-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME LLC (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230174567-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME LLC (US) | 2023-06-08 | — | — | US | disclosed |
| US-11344646-B2 | Use of fluorescent polymers in marking compositions for the diagnostic determination of cleaning performance | ECOLAB USA INC. (US) | 2022-05-31 | — | — | US | disclosed |
| US-20210275710-A1 | USE OF FLUORESCENT POLYMERS IN MARKING COMPOSITIONS FOR THE DIAGNOSTIC DETERMINATION OF CLEANING PERFORMANCE | ECOLAB USA INC (US) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230287032-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | NUDT1, NT5C3B, DUT | CYP2D6 922/4885KDM4E 2751/4885ALDH1A1 1354/4885 |
| US-20230174567-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | NUDT1, NT5C3B, MTAP | CYP2D6 1067/4885KDM4E 2479/4885ALDH1A1 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.