Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.50 |
| ▸ | AANAT | Q16613 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2380275 | 0.99 | BCHE (0.54) | BCHEACHEOPRM1OPRL1AANAT | |
| SCHEMBL2379029 | 0.86 | OPRL1 (0.67) | BCHEACHEOPRM1OPRL1AANAT | |
| Hydrochloric Acid SCHEMBL302553 | 0.85 | OPRL1 (0.68) | BCHEACHEOPRM1OPRL1AANAT | |
| SCHEMBL2378445 | 0.83 | OPRL1 (0.58) | BCHEACHEOPRM1OPRL1AANAT | |
| Hydrochloric Acid SCHEMBL2380103 | 0.82 | OPRL1 (0.58) | BCHEACHEOPRM1OPRL1AANAT | |
| SCHEMBL5197985 | 0.82 | OPRL1 (0.73) | BCHEOPRM1OPRL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5197976 | 0.82 | OPRL1 (0.73) | BCHEOPRM1OPRL1MEN1KMT2A | |
| SCHEMBL2379196 | 0.81 | OPRL1 (0.62) | BCHEACHEOPRM1OPRL1MTNR1A | |
| SCHEMBL2379116 | 0.81 | MAPT (0.60) | BCHEACHEOPRM1OPRL1MAPT | |
| SCHEMBL2379673 | 0.81 | MEN1 (0.47) | OPRM1OPRL1AANATMTNR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | claimed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | claimed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1751093-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110976-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129347-A1 | Cyclohexylacetic acid compounds | ACACA, HCAR2, PCCA | BCHE 806/4885ACHE 2142/4885OPRM1 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.