Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968221 | 0.82 | GAA (0.44) | ALDH1A1POLBGAATHRBEGLN1 | |
| SCHEMBL11621614 | 0.79 | PDE4A (0.38) | ALDH1A1POLBADRB2 | |
| SCHEMBL1610816 | 0.77 | GAA (0.34) | ALDH1A1POLBGAATHRBFFAR4 | |
| SCHEMBL30636513 | 0.76 | GPR3 (0.41) | ALDH1A1POLBGAATHRBMAOB | |
| SCHEMBL16952446 | 0.76 | GPR3 (0.41) | ALDH1A1POLBGAATHRBMAOB | |
| SCHEMBL18615589 | 0.74 | MAPT (0.38) | MAOBAOC3PTGS1PTGS2 | |
| SCHEMBL14676282 | 0.74 | CA1 (0.42) | ALDH1A1POLBGAATHRB | |
| SCHEMBL21603490 | 0.74 | PTGS1 (0.34) | ALDH1A1POLBGAATHRBFFAR4 | |
| SCHEMBL19643366 | 0.74 | CA1 (0.42) | ALDH1A1POLBGAATHRB | |
| SCHEMBL29778859 | 0.74 | CA1 (0.42) | ALDH1A1POLBGAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272036-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-3877356-A1 | BICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| CN-113302175-A | Bicyclic compounds | 维瓦斯治疗公司 | 2021-08-24 | — | — | CN | disclosed |