SCHEMBL968221

SCHEMBL968221

Nc1c(Br)cc(OC(F)(F)F)cc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.44
MAPT P10636 3/20 0.44
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
CA3 P07451 1/20 0.37
POLB P06746 2/20 0.36
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1610816 0.90 GAA (0.34) GAAMAPTCA1CA2CA9
SCHEMBL14676282 0.86 CA1 (0.42) GAAMAPTCA1CA2CA9
SCHEMBL19643366 0.86 CA1 (0.42) GAAMAPTCA1CA2CA9
SCHEMBL21603490 0.86 PTGS1 (0.34) GAAMAPTPOLBALDH1A1THRB
SCHEMBL29778859 0.86 CA1 (0.42) GAAMAPTCA1CA2CA9
SCHEMBL23796052 0.82 GAA (0.36) GAAPOLBALDH1A1THRBNPC1
SCHEMBL23796403 0.82 ALDH1A1 (0.33) GAAPOLBALDH1A1THRBEGLN1
SCHEMBL16529505 0.80 WDR5 (0.42) GAAPOLBALDH1A1THRBHSD17B10
SCHEMBL30577358 0.80 ALDH1A1 (0.53) GAAMAPTPOLBALDH1A1THRB
SCHEMBL1192876 0.80 ALDH1A1 (0.53) GAAMAPTPOLBALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751376-A Preparation method of thifluzamide 广东禾康精细化工有限公司 2025-04-04 CN claimed
CN-117049969-A Preparation method of 2, 6-dibromo-4-trifluoromethoxy aniline 阜新睿光氟化学有限公司 2023-11-14 CN claimed
CN-114560825-A Preparation method and application of benzisothiazole compound for preventing and treating rice stem borer 广西师范大学 2022-05-31 CN claimed
CN-114516806-A Preparation method of 2, 6-dibromo-4-trifluoromethoxy aniline 阜新都创新材料科技有限公司 2022-05-20 CN claimed
WO-2005100434-A1 HALOGEN CONTAINING EPOXY COMPOSITIONS AND THEIR PREPARATION UNIVERSITY OF NORTH TEXAS (US) 2005-10-27 WO claimed
US-20050228080-A1 Halogen containing epoxy compositions and their preparation UNIVERSITY OF NORTH TEXAS (US) 2005-10-13 US claimed
US-6114584-A Method of preparing brominated substituted anilines OCCIDENTAL CHEMICAL CORPORATION (US) 2000-09-05 US claimed
CN-119591560-B Synthesis method of thifluzamide 湖南速博生物技术有限公司 2025-04-29 CN disclosed
CN-119751376-A Preparation method of thifluzamide 广东禾康精细化工有限公司 2025-04-04 CN disclosed
CN-119751376-A Preparation method of thifluzamide 广东禾康精细化工有限公司 2025-04-04 CN disclosed
CN-119591560-A Synthesis method of thifluzamide 湖南速博生物技术有限公司 2025-03-11 CN disclosed
WO-2024057013-A1 NLRP3 MODULATORS EXSCIENTIA AI LIMITED (GB) 2024-03-21 WO disclosed
CN-117049969-A Preparation method of 2, 6-dibromo-4-trifluoromethoxy aniline 阜新睿光氟化学有限公司 2023-11-14 CN disclosed
US-7868067-B2 Composition of epoxy resin, aliphatic amine curing agent and halogenated amine UNIVERSITY OF NORTH TEXAS (US) 2011-01-11 US disclosed
US-20090176932-A1 Halogen containing epoxy compositions and their preparation UNIVERSITY OF NORTH TEXAS (US) 2009-07-09 US disclosed
US-7501461-B2 Composition of epoxy resin, aliphatic amine curing agent and halogenated amine UNIVERSITY OF NORTH TEXAS (US) 2009-03-10 US disclosed
WO-2005100434-A1 HALOGEN CONTAINING EPOXY COMPOSITIONS AND THEIR PREPARATION UNIVERSITY OF NORTH TEXAS (US) 2005-10-27 WO disclosed
US-20050228080-A1 Halogen containing epoxy compositions and their preparation UNIVERSITY OF NORTH TEXAS (US) 2005-10-13 US disclosed
JP-2001199943-A METHOD FOR PRODUCING 2,6-DIBROMO-4- TRIFLUOROMETHOXYANILINE KEMIKUREA:KK 2001-07-24 JP disclosed
US-6114584-A Method of preparing brominated substituted anilines OCCIDENTAL CHEMICAL CORPORATION (US) 2000-09-05 US disclosed