SCHEMBL23797015

SCHEMBL23797015

C=CCSS/C=C/C[S+]([O-])Cc1ccc(C(F)(F)F)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.33
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23796922 1.00 PTGS2 (0.33) PTGS2IDO1
SCHEMBL12362845 0.83 PTGS2 (0.35) PTGS2
SCHEMBL19785654 0.83 PTGS2 (0.36) PTGS2
SCHEMBL1841062 0.80 TP53 (0.41) PTGS2IDO1
SCHEMBL1841064 0.80 TP53 (0.41) PTGS2IDO1
SCHEMBL24188622 0.79 TAAR1 (0.39) IDO1
SCHEMBL23796904 0.78 MEN1 (0.37) IDO1
SCHEMBL23796902 0.78 MEN1 (0.37) IDO1
SCHEMBL23796535 0.76 IDO1 (0.38) PTGS2IDO1
SCHEMBL23796537 0.76 IDO1 (0.38) PTGS2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312301-B2 Organosulfur compounds MARIPOSA THERAPEUTICS LTD. (GB) 2025-05-27 US disclosed
US-20220009882-A1 ORGANOSULFUR COMPOUNDS MARIPOSA THERAPEUTICS LTD. (GB) 2022-01-13 US disclosed
EP-3877362-A1 ORGANOSULFUR COMPOUNDS Mariposa Therapeutics Ltd. (GB) 2021-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009882-A1 ORGANOSULFUR COMPOUNDS F3, F2, TST PTGS2 121/4885IDO1 2059/4885
US-12312301-B2 Organosulfur compounds TST, MPST, F2 PTGS2 78/4885IDO1 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.