SCHEMBL1082345

SCHEMBL1082345

NC(N)=CCN1CCNCC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.34
POLB P06746 1/20 0.34
CXCR4 P61073 2/20 0.33
SIGMAR1 Q99720 3/20 0.32
CHRM5 P08912 2/20 0.32
CHRM3 P20309 2/20 0.32
ANPEP P15144 1/20 0.31
ERAP2 Q6P179 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1234464 0.79 SIGMAR1 (0.38) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL9404145 0.77 GBA1 (0.43) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL7741819 0.74 HRH3 (0.34) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL4559034 0.74 CHRM5 (0.38) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL11393659 0.73
SCHEMBL7710812 0.72 MEN1 (0.35) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL7706864 0.72 MEN1 (0.35) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL7706868 0.72 MEN1 (0.35) HSD17B10SMN1; SMN2POLBCXCR4SIGMAR1
Urea SCHEMBL10753125 0.72 NPC1 (0.39) HSD17B10SIGMAR1CHRM5CHRM3ANPEP
SCHEMBL23798166 0.71 MEN1 (0.37) HSD17B10SMN1; SMN2POLBSIGMAR1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423554-A1 LUBRICATING OIL COMPOSITION HAVING IMPROVED AIR RELEASE The Lubrizol Corporation (US) 2019-01-09 EP disclosed
EP-3320060-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING ENGINE KNOCK AND PRE-IGNITION IN HIGH COMPRESSION SPARK IGNITION ENGINES ExxonMobil Research and Engineering Company (US) 2018-05-16 EP disclosed
WO-2017007670-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING ENGINE KNOCK AND PRE-IGNITION IN HIGH COMPRESSION SPARK IGNITION ENGINES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-01-12 WO disclosed
EP-2483379-A1 ALKYLATED NAPHTHALENE BASE STOCK LUBRICANT FORMULATIONS ExxonMobil Research and Engineering Company (US) 2012-08-08 EP disclosed
WO-2012058204-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-05-03 WO disclosed
EP-2334771-A1 LOW SULFUR AND LOW METAL ADDITIVE FORMULATIONS FOR HIGH PERFORMANCE INDUSTRIAL OILS ExxonMobil Research and Engineering Company (US) 2011-06-22 EP disclosed
WO-2011041647-A1 ALKYLATED NAPHTHALENE BASE STOCK LUBRICANT FORMULATIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-04-07 WO disclosed
EP-2288681-A2 LUBRICANT COMPOSITION WITH IMPROVED VARNISH DEPOSIT RESISTANCE ExxonMobil Research and Engineering Company (US) 2011-03-02 EP disclosed
EP-2288680-A2 UNEXPECTED SHEAR STABILITY BENEFITS OF SYNTHETIC OILS AND VISCOSITY MODIFIER COMBINATIONS ExxonMobil Research and Engineering Company (US) 2011-03-02 EP disclosed
EP-2271734-A2 HIGH VISCOSITY INDEX PAO WITH POLYUREA THICKENERS IN GREASE COMPOSITIONS ExxonMobil Research and Engineering Company (US) 2011-01-12 EP disclosed
WO-2009145825-A2 HIGH VISCOSITY INDEX PAO WITH POLYUREA THICKENERS IN GREASE COMPOSITIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-12-03 WO disclosed
WO-2009145824-A2 LUBRICANT COMPOSITION WITH IMPROVED VARNISH DEPOSIT RESISTANCE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-12-03 WO disclosed
WO-2009145823-A2 UNEXPECTED SHEAR STABILITY BENEFITS OF SYNTHETIC OILS AND VISCOSITY MODIFIER COMBINATIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-12-03 WO disclosed
EP-2041050-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS ExxonMobil Research and Engineering Company (US) 2009-04-01 EP disclosed
EP-2038386-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS ExxonMobil Research and Engineering Company (US) 2009-03-25 EP disclosed
JP-2008074969-A ADHESIVE COMPOSITION TORAY FINE CHEMICALS CO LTD 2008-04-03 JP disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007017623-A1 CLEANING COMPOSITIONS AND METHODS RECKITT BENCKISER (UK) LIMITED (GB) 2007-02-15 WO disclosed
WO-2000051945-A1 METHOD FOR INHIBITING THE FORMATION AND DEPOSITION OF SILICA SCALE IN WATER SYSTEMS NALCO CHEMICAL COMPANY (US) 2000-09-08 WO disclosed