SCHEMBL23802448

SCHEMBL23802448

CCOC(=O)Oc1ccc(C(=O)c2ccc3c(c2)c2cc(C(=O)/C(=N/OC)C4CCCC4)ccc2n3CC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 4/20 0.38
RAB9A P51151 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36
TUBB6 Q9BUF5 1/20 0.36
TUBB2B Q9BVA1 1/20 0.36
TUBB1 Q9H4B7 1/20 0.36
PTGER4 P35408 2/20 0.36
KDM2B Q8NHM5 2/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23802447 0.92 RORC (0.37) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23802121 0.92 RORC (0.37) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23801351 0.84 KDM4E (0.38) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23801799 0.78 RORC (0.47) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23802115 0.78 HPGD (0.39) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23802159 0.78 HPGD (0.39) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23802439 0.77 TUBB4A (0.38) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL25521961 0.77 RORC (0.34) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23802116 0.76 KDM4E (0.45) RORCRAB9ATUBB4ATUBBTUBA3C
SCHEMBL23801803 0.75 CNR2 (0.41) RORCTUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021175855-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-09-10 WO disclosed