Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23804607 | 0.80 | HSPA5 (0.74) | SMN1; SMN2LMNA | |
| SCHEMBL23804615 | 0.80 | HSPA5 (0.74) | SMN1; SMN2LMNA | |
| SCHEMBL13753488 | 0.78 | RAB9A (0.62) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL23804599 | 0.78 | CASP3 (0.69) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL1929165 | 0.77 | NPC1 (0.85) | KMT2ARAB9ANPC1MEN1TDP1 | |
| SCHEMBL23804610 | 0.77 | HSPA5 (0.76) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL23804609 | 0.77 | HSPA5 (0.49) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL23804597 | 0.77 | MAPT (0.47) | KMT2AL3MBTL1RAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL31228835 | 0.76 | NPC1 (0.82) | KMT2ARAB9ANPC1MEN1TDP1 | |
| SCHEMBL12376694 | 0.74 | RAB9A (0.66) | KMT2ARAB9ANPC1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183942-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-09-16 | — | — | WO | disclosed |