Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.42 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23804599 | 0.77 | CASP3 (0.69) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL23804609 | 0.77 | HSPA5 (0.49) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23804619 | 0.77 | KMT2A (0.54) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9891923 | 0.75 | KDM4E (0.59) | MAPTKMT2AMEN1SCDRAB9A | |
| SCHEMBL23804607 | 0.73 | HSPA5 (0.74) | SMN1; SMN2HSPA5HSPA9HSPA2 | |
| SCHEMBL23804615 | 0.73 | HSPA5 (0.74) | SMN1; SMN2HSPA5HSPA9HSPA2 | |
| SCHEMBL23804610 | 0.73 | HSPA5 (0.76) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13753488 | 0.72 | RAB9A (0.62) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL11410245 | 0.68 | SCD (0.60) | MAPTKMT2AMEN1SCDRAB9A | |
| SCHEMBL4477605 | 0.68 | RAB9A (0.61) | MAPTKMT2AMEN1SCDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183942-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-09-16 | — | — | WO | disclosed |