SCHEMBL25214713

SCHEMBL25214713

O=C(C=Cc1ccc(O)c(Br)c1)c1ccc(F)cc1F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
NPSR1 Q6W5P4 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SNCA P37840 1/20 0.55
MAOB P27338 3/20 0.54
ACHE P22303 1/20 0.54
BACE1 P56817 1/20 0.54
PRMT1 Q99873 1/20 0.52
CXCL12 P48061 1/20 0.52
LMNA P02545 2/20 0.51
ALDH1A1 P00352 1/20 0.51
TP53 P04637 1/20 0.51
P4HB P07237 2/20 0.51
MKNK2 Q9HBH9 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HPGD P15428 1/20 0.50
MAOA P21397 1/20 0.49
TERT O14746 1/20 0.49
CTSL P07711 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25197224 1.00 MAPT (0.58) MAPTNPSR1L3MBTL1SNCAMAOB
SCHEMBL30384947 1.00 MAPT (0.58) MAPTNPSR1L3MBTL1SNCAMAOB
SCHEMBL30384093 1.00 MAPT (0.58) MAPTNPSR1L3MBTL1SNCAMAOB
SCHEMBL25218131 0.84 MAOB (0.61) MAPTNPSR1L3MBTL1MAOBBACE1
SCHEMBL31233418 0.84 MAOB (0.61) MAPTNPSR1L3MBTL1MAOBBACE1
SCHEMBL31233147 0.84 MAOB (0.61) MAPTNPSR1L3MBTL1MAOBBACE1
SCHEMBL25231544 0.84 MAOB (0.61) MAPTNPSR1L3MBTL1MAOBBACE1
SCHEMBL25195977 0.82 MKNK2 (0.69) MAPTNPSR1L3MBTL1SNCAACHE
SCHEMBL31233251 0.81 CYP3A4 (0.62) MAPTNPSR1L3MBTL1MAOBBACE1
SCHEMBL23804649 0.81 CYP3A4 (0.62) MAPTNPSR1L3MBTL1MAOBBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885NPSR1 4347/4885L3MBTL1 3658/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885NPSR1 4282/4885L3MBTL1 2560/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885NPSR1 4282/4885L3MBTL1 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.