Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 4/20 | 0.33 |
| ▸ | CHUK | O15111 | 4/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995163 | 0.78 | AHR (0.48) | AHRCYP2A6NR4A2PIM3IKBKB | |
| SCHEMBL16815127 | 0.78 | IKBKB (0.35) | AHRCYP2A6NR4A2IKBKBCHUK | |
| SCHEMBL26389475 | 0.77 | AHR (0.47) | AHRCYP2A6NR4A2PIM3IKBKB | |
| SCHEMBL15388774 | 0.77 | AHR (0.47) | AHRALDH1A1IKBKBCHUKJAK2 | |
| SCHEMBL3584001 | 0.75 | AHR (0.45) | AHRCYP2A6NR4A2PIM3IKBKB | |
| SCHEMBL28783304 | 0.75 | AHR (0.45) | AHRCYP2A6NR4A2PIM3IKBKB | |
| SCHEMBL564695 | 0.75 | AHR (0.50) | AHRCYP2A6NR4A2PIM3IKBKB | |
| SCHEMBL120501 | 0.75 | AHR (0.45) | AHRCYP2A6NR4A2PIM3CSNK2A1 | |
| SCHEMBL30391792 | 0.75 | AHR (0.45) | AHRCYP2A6NR4A2PIM3CSNK2A1 | |
| SCHEMBL15934119 | 0.75 | TDP1 (0.38) | AHRCYP2A6KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613752-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| US-20250270224-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2025-08-28 | — | — | US | disclosed |
| EP-3492474-B1 | INTERMEDIATES USED IN THE PRODUCTION OF DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-3492474-B1 | INTERMEDIATES USED IN THE PRODUCTION OF DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-2968272-B1 | USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING | ALEVERE MEDICAL CORP (US) | 2021-06-16 | — | — | EP | disclosed |
| EP-2968272-B1 | USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING | ALEVERE MEDICAL CORP (US) | 2021-06-16 | — | — | EP | disclosed |
| US-10653670-B2 | Use of indole compounds for fat reduction and skin and soft tissue tightening | ALEVERE MEDICAL CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-10653670-B2 | Use of indole compounds for fat reduction and skin and soft tissue tightening | ALEVERE MEDICAL CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| EP-3031928-B1 | QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS | BIO RAD INNOVATIONS (FR) | 2019-11-20 | — | — | EP | disclosed |
| US-20190290613-A1 | USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING | ALEVERE MEDICAL CORPORATION | 2019-09-26 | — | — | US | disclosed |
| EP-2542688-A1 | QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS | Bio-Rad Innovations (FR) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107703-A1 | QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS | BIO-RAD PASTEUR (FR) | 2011-09-09 | — | — | WO | disclosed |
| US-20100179123-A1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2010-07-15 | — | — | US | disclosed |
| US-7601725-B2 | Thienopyrimidines useful as Aurora kinase inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601725-B2 | Thienopyrimidines useful as Aurora kinase inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | HAFFNER CURT D | 2007-05-03 | — | — | US | disclosed |
| US-7173134-B2 | Selective RXR ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040198980-A1 | Selective rxr ligands | SMITHKLINE BEECHAM CORPORATION | 2004-10-07 | — | — | US | disclosed |
| EP-1430042-A2 | BICYCLIC HETEROCYCLES AS RXR LIGANDS | SmithKline Beecham Corporation (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003027090-A2 | BICYCLIC HETEROCYCLES AS RXR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198980-A1 | Selective rxr ligands | RXRA, RXRB, RXRG | AHR 284/4885CYP2A6 669/4885NR4A2 17/4885 |
| US-20250270224-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | PARP1, PARP11, PARP2 | AHR 2665/4885CYP2A6 2352/4885NR4A2 4708/4885 |
| US-20190290613-A1 | USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING | IDO1, FABP4, IDO2 | AHR 68/4885CYP2A6 2354/4885NR4A2 3975/4885 |
| US-20100179123-A1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | AURKA, AURKB, AURKC | AHR 2895/4885CYP2A6 3556/4885NR4A2 2678/4885 |
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | RXRB, RXRA, RXRG | AHR 255/4885CYP2A6 775/4885NR4A2 20/4885 |
| US-10653670-B2 | Use of indole compounds for fat reduction and skin and soft tissue tightening | IDO1, FABP4, IDO2 | AHR 68/4885CYP2A6 2354/4885NR4A2 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.