Sugi Predict

Sugi Predict / Compounds / SCHEMBL120501

SCHEMBL120501

SCHEMBL120501

Fc1cc(Br)cc2cc[nH]c12

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 5/20 0.45
▸ CYP2A6 P11509 1/20 0.45
▸ NR4A2 P43354 1/20 0.45
▸ TNF P01375 1/20 0.42
▸ RIPK1 Q13546 1/20 0.42
▸ GPR84 Q9NQS5 1/20 0.42
▸ PIM3 Q86V86 1/20 0.38
▸ CSNK2A1 P68400 1/20 0.37
▸ SLC6A2 P23975 9/20 0.35
▸ SLC6A4 P31645 9/20 0.35
▸ SLC6A3 Q01959 9/20 0.35
▸ CYP2D6 P10635 8/20 0.35
▸ KCNH2 Q12809 1/20 0.35
▸ NT5E P21589 1/20 0.34
▸ DGAT1 O75907 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30391792 1.00 AHR (0.45) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL2537652 0.80 AHR (0.50) AHRTNFRIPK1GPR84SLC6A2
SCHEMBL8995163 0.78 AHR (0.48) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL26389475 0.77 AHR (0.47) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL794596 0.77 TNF (0.44) AHRTNFRIPK1GPR84CSNK2A1
SCHEMBL3584001 0.75 AHR (0.45) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL2380876 0.75 AHR (0.45) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL28783304 0.75 AHR (0.45) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL564695 0.75 AHR (0.50) AHRCYP2A6NR4A2TNFRIPK1
SCHEMBL3961345 0.75 TNF (0.42) AHRTNFRIPK1GPR84SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805664-B Bionic modified marine antifouling resin material, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2023-04-14 — — CN claimed
CN-114805664-A Bionic modified marine antifouling resin material, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-07-29 — — CN claimed
CN-114292582-B Hyperbranched coating suitable for marine concrete, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-07-12 — — CN claimed
CN-114292582-A Hyperbranched coating suitable for marine concrete, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-04-08 — — CN claimed
WO-2026086928-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2026-04-30 — — WO disclosed
EP-4703359-A1 IMIDAZOPYRIDINE OR IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Shanghai Simr Biotechnology Co., Ltd. (CN) 2026-03-04 — — EP disclosed
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
CN-119161324-A Methods and compounds for restoring mutant p53 function 皮姆维制药公司 2024-12-20 — — CN disclosed
WO-2024182788-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2024-09-06 — — WO disclosed
CN-118515663-A Imidazopyridine or imidazopyrazine compounds, preparation method, pharmaceutical composition and application thereof 上海赛默罗生物科技有限公司 2024-08-20 — — CN disclosed
US-20240262838-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2024-08-08 — — US disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 — — WO disclosed
US-20090099236-A1 3-Amino-1-arylpropyl indoles and AZA-substituted indoles and uses thereof ROCHE PALO ALTO LLC 2009-04-16 — — US disclosed
CN-101316818-A 3-amino-1-arylpropyl indoles and aza-substituted indoles HOFFMANN LA ROCHE (CH) 2008-12-03 — — CN disclosed
US-7446118-B2 3-amino-1-arylpropyl indoles and aza-substituted indoles and uses thereof ROCHE PALO ALTO LLC (US) 2008-11-04 — — US disclosed
EP-1960355-A1 3-AMINO-1-ARYLPROPYL INDOLES AND AZA-SUBSTITUTED INDOLES F.HOFFMANN-LA ROCHE AG (CH) 2008-08-27 — — EP disclosed
WO-2008019971-A2 ARYLPIPERAZINE DERIVATIVES AND USES THEREOF F. HOFFMANN-LA ROCHE AG (CH) 2008-02-21 — — WO disclosed
US-20080045543-A1 Arylpiperazine derivatives and uses thereof ROCHE PALO ALTO LLC 2008-02-21 — — US disclosed
WO-2007062996-A1 3-AMINO-1-ARYLPROPYL INDOLES AND AZA-SUBSTITUTED INDOLES F. HOFFMANN-LA ROCHE AG (CH) 2007-06-07 — — WO disclosed
US-20070123527-A1 3-Amino-1-arylpropyl indoles and aza-substituted indoles and uses thereof ROCHE PALO ALTO LLC 2007-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123527-A1 3-Amino-1-arylpropyl indoles and aza-substituted indoles and uses thereof IDO1, RB1, AHR AHR 3/4885CYP2A6 74/4885NR4A2 366/4885
US-20090099236-A1 3-Amino-1-arylpropyl indoles and AZA-substituted indoles and uses thereof IDO1, RB1, AHR AHR 3/4885CYP2A6 74/4885NR4A2 366/4885
US-20240262838-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF NPR1, NPR3, NUCB2 AHR 88/4885CYP2A6 864/4885NR4A2 29/4885
US-20080045543-A1 Arylpiperazine derivatives and uses thereof CYP3A7, CYP3A5, HTR7 AHR 6/4885CYP2A6 129/4885NR4A2 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.