SCHEMBL23808908

SCHEMBL23808908

Nc1cc(Cl)cc(-c2cccc(O)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 9/20 0.52
HSD17B2 P37059 8/20 0.52
CYP3A4 P08684 4/20 0.52
CYP2C9 P11712 3/20 0.52
CYP1A2 P05177 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2B6 P20813 2/20 0.48
CYP2C19 P33261 2/20 0.48
TSHR P16473 1/20 0.47
CA12 O43570 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA14 Q9ULX7 1/20 0.47
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
RXRA P19793 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21296916 0.86 HSD17B1 (0.62) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL31544769 0.86 HSD17B1 (0.62) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL24642598 0.84 HSD17B1 (0.60) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL30469326 0.80 CA12 (0.73) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL29441691 0.80 CA12 (0.73) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL2462229 0.80 CA12 (0.73) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL1029061 0.80 TSHR (0.73) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL14128677 0.78 MAOA (0.54) CYP3A4CYP1A2ALDH1A1TDP1RXRA
Hydrochloric Acid SCHEMBL2462962 0.78 CA12 (0.70) HSD17B1HSD17B2CYP3A4CYP2C9CYP1A2
SCHEMBL20557903 0.78 MAOA (0.60) CYP3A4CA12ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3326715-B1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE CE PHARM CO LTD (CN) 2021-09-15 EP disclosed