Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 6/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720908 | 0.83 | FDPS (0.47) | ALDH1A1CYP1A2POLBFDPSCCR2 | |
| SCHEMBL23809128 | 0.82 | CCR2 (0.42) | ALDH1A1CYP1A2POLBFDPSCCR2 | |
| SCHEMBL6838172 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP1A2POLBTSHRHTT | |
| SCHEMBL6839017 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP1A2POLBTSHRHTT | |
| SCHEMBL23809361 | 0.80 | CCR2 (0.58) | FDPSCCR2CCR9 | |
| SCHEMBL23809274 | 0.79 | CCR2 (0.40) | ALDH1A1CYP1A2POLBFDPSCCR2 | |
| SCHEMBL23809126 | 0.78 | FDPS (0.42) | ALDH1A1CYP1A2POLBFDPSCCR2 | |
| SCHEMBL23809305 | 0.77 | CCR9 (0.44) | ALDH1A1CYP1A2POLBFDPSCCR2 | |
| SCHEMBL6750523 | 0.76 | ALDH1A1 (0.97) | ALDH1A1CYP1A2POLBTSHRHTT | |
| SCHEMBL23809513 | 0.75 | CCR2 (0.40) | ALDH1A1CYP1A2POLBFDPSCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283138-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | VANDERBILT UNIVERSITY | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283138-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, BCL9 | ALDH1A1 2556/4885CYP1A2 4125/4885POLB 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.