Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23810437 | 0.80 | MMP13 (0.45) | MMP1MMP9MMP13GPR119APLNR | |
| SCHEMBL23795420 | 0.80 | MMP13 (0.45) | MMP1MMP9MMP13GPR119APLNR | |
| SCHEMBL24178165 | 0.73 | MMP13 (0.43) | MMP1MMP9MMP13PARP1APLNR | |
| SCHEMBL30439175 | 0.73 | MMP13 (0.43) | MMP1MMP9MMP13PARP1APLNR | |
| SCHEMBL23795403 | 0.73 | MMP13 (0.43) | MMP1MMP9MMP13PARP1APLNR | |
| SCHEMBL24177988 | 0.71 | MMP13 (0.41) | MMP1MMP9MMP13GPR119APLNR | |
| SCHEMBL23795385 | 0.71 | MMP13 (0.41) | MMP1MMP9MMP13GPR119APLNR | |
| SCHEMBL23810433 | 0.70 | HTR6 (0.38) | MMP1MMP9MMP13PARP1APLNR | |
| SCHEMBL31399710 | 0.69 | ALDH1A1 (0.49) | ACHE | |
| SCHEMBL23795306 | 0.69 | CNR1 (0.44) | SMARCA2SMARCA4PBRM1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3878846-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | Beijing Increase Innovative Drug Co., Ltd. (CN) | 2021-09-15 | — | — | EP | disclosed |