Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23812331 | 0.83 | HSD17B10 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21534157 | 0.81 | SIGMAR1 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20739323 | 0.80 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19954996 | 0.80 | POLB (0.37) | SMN1; SMN2HSD17B10SIGMAR1POLBCXCR4 | |
| SCHEMBL845511 | 0.78 | HSD17B10 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24278279 | 0.78 | MEN1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22590607 | 0.78 | HSD17B10 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20328752 | 0.78 | SIGMAR1 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21534190 | 0.77 | RAD52 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29860764 | 0.76 | HSD17B10 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3469012-B9 | AUTOCATALYTIC POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-04-06 | — | — | EP | disclosed |
| EP-3469012-B1 | AUTOCATALYTIC POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-09-15 | — | — | EP | disclosed |