Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24278279 | 0.94 | MEN1 (0.32) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL23812243 | 0.83 | MEN1 (0.40) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21534157 | 0.69 | SIGMAR1 (0.38) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL20739323 | 0.69 | MEN1 (0.48) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL19954996 | 0.68 | POLB (0.37) | HSD17B10SMN1; SMN2SIGMAR1 | |
| SCHEMBL845511 | 0.67 | HSD17B10 (0.57) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL20328752 | 0.67 | SIGMAR1 (0.51) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21534190 | 0.66 | RAD52 (0.37) | HSD17B10SMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL29860764 | 0.66 | HSD17B10 (0.55) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL19619099 | 0.65 | HSD17B10 (0.47) | HSD17B10ANPEPERAP2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3469012-B1 | AUTOCATALYTIC POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-09-15 | — | — | EP | disclosed |