Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.94 |
| ▸ | TLR4 | O00206 | 1/20 | 0.54 |
| ▸ | TLR3 | O15455 | 1/20 | 0.54 |
| ▸ | TLR5 | O60602 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.54 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.54 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.54 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.54 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.54 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.54 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27125003 | 0.84 | TLR8 (0.73) | TLR8TLR4TLR3TLR5TLR2 | |
| SCHEMBL20436901 | 0.78 | TLR8 (1.00) | TLR8 | |
| SCHEMBL901543 | 0.77 | TLR8 (0.61) | TLR8 | |
| SCHEMBL5283927 | 0.76 | TLR8 (0.60) | TLR8 | |
| SCHEMBL5291087 | 0.76 | TLR8 (0.60) | TLR8 | |
| SCHEMBL5287379 | 0.76 | TLR8 (0.60) | TLR8 | |
| SCHEMBL5300299 | 0.76 | TLR8 (0.60) | TLR8 | |
| SCHEMBL5291339 | 0.76 | TLR8 (0.60) | TLR8 | |
| SCHEMBL5812027 | 0.76 | TLR8 (0.60) | TLR8 | |
| SCHEMBL5301102 | 0.76 | TLR8 (0.60) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283107-A1 | Methods to Expand the Spectrum of Gram-Positive Antibiotics | UNIV NORTH CAROLINA STATE (US) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283107-A1 | Methods to Expand the Spectrum of Gram-Positive Antibiotics | RPN2, RPN1, MGAM | TLR8 188/4885TLR4 177/4885TLR3 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.