Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.61 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.45 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902288 | 0.80 | ALDH1A1 (0.50) | TLR8BACE1ALDH1A1HTR6 | |
| SCHEMBL28882126 | 0.80 | TLR8 (0.48) | TLR8LTB4RADORA2AADORA1ALDH1A1 | |
| SCHEMBL14415476 | 0.77 | TLR8 (0.49) | TLR8LTB4RADORA2AADORA1ALDH1A1 | |
| SCHEMBL23812475 | 0.77 | TLR8 (0.94) | TLR8 | |
| SCHEMBL4149124 | 0.73 | BACE1 (0.76) | TLR8LTB4RBACE1 | |
| SCHEMBL2022025 | 0.69 | ADORA2A (0.62) | TLR8LTB4RADORA2AADORA1BACE1 | |
| SCHEMBL9409256 | 0.67 | LTB4R (0.45) | TLR8LTB4RADORA2AADORA1ADCY10 | |
| SCHEMBL5814723 | 0.67 | NOS3 (0.43) | TLR8LTB4R | |
| SCHEMBL9914071 | 0.67 | MAOA (0.54) | TLR8ALDH1A1BRD4HRH4 | |
| SCHEMBL1045329 | 0.67 | TLR8 (0.49) | TLR8ADORA2AADORA1ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | claimed |
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | disclosed |
| CN-1060173-C | Heterocyclic compound with activity against diabetes and preparation and application of same | MITSUTAKA CO LTD (JP) | 2001-01-03 | — | — | CN | disclosed |
| CN-1118781-A | Heterocyclic compound with activity against diabetes and preparation and application of same | MITSUTAKA CO LTD (JP) | 1996-03-20 | — | — | CN | disclosed |