Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.36 |
| ▸ | GLP1R | P43220 | 8/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | GART | P22102 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23802684 | 0.85 | PTGS1 (0.41) | NOD1GLP1RFOLH1 | |
| SCHEMBL23802686 | 0.85 | PTGS1 (0.41) | NOD1GLP1RFOLH1 | |
| SCHEMBL22044568 | 0.76 | PTGS1 (0.36) | FOLH1 | |
| SCHEMBL30396692 | 0.76 | FOLH1 (0.32) | NOD1FOLH1 | |
| SCHEMBL18626096 | 0.76 | NOD1 (0.40) | NOD1FOLH1 | |
| SCHEMBL27450827 | 0.74 | PTGS1 (0.40) | NOD1FOLH1GART | |
| SCHEMBL24864576 | 0.74 | PTGS1 (0.39) | — | |
| SCHEMBL22852572 | 0.73 | NPSR1 (0.34) | NOD1FOLH1GART | |
| SCHEMBL21727091 | 0.73 | FAAH (0.43) | — | |
| SCHEMBL15877247 | 0.73 | NOD1 (0.42) | NOD1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029736-B2 | Camptothecin derivatives and conjugates thereof | MEDIBOSTON LIMITED (HK) | 2024-07-09 | — | — | US | disclosed |
| US-20210283125-A1 | CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | FORTVITA BIOLOGICS LIMITED (CN) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283125-A1 | CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | TOP2A, TOP1, XPA | NOD1 517/4885GLP1R 1610/4885FOLH1 708/4885 |
| US-12029736-B2 | Camptothecin derivatives and conjugates thereof | TOP2A, TOP1, XPA | NOD1 517/4885GLP1R 1610/4885FOLH1 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.