Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864492 | 0.88 | PTGS1 (0.49) | PTGS1PTGS2SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL27292160 | 0.88 | PTGS1 (0.49) | PTGS1PTGS2SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL22044568 | 0.87 | PTGS1 (0.36) | PTGS1PTGS2SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL23583708 | 0.78 | MEN1 (0.45) | PTGS1PTGS2SMN1; SMN2ALDH1A1FAAH | |
| SCHEMBL22238251 | 0.78 | EPHX2 (0.35) | PTGS1PTGS2SMN1; SMN2ALDH1A1FAAH | |
| SCHEMBL21610368 | 0.76 | MGLL (0.59) | PTGS1PTGS2SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL19851854 | 0.76 | MGLL (0.59) | PTGS1PTGS2SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL22388826 | 0.76 | NOD1 (0.39) | SMN1; SMN2FAAHNPSR1LMNAMAPK1 | |
| SCHEMBL22223321 | 0.75 | PTGS1 (0.61) | PTGS1PTGS2SMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL21727091 | 0.75 | FAAH (0.43) | PTGS1PTGS2SMN1; SMN2ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |