SCHEMBL2381633

SCHEMBL2381633

CC(=C[Si](C)(C)C)C(=O)OCCO

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.32
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642491 0.84 HCAR2 (0.38) TSHRALDH1A1
SCHEMBL19582862 0.81 ALDH1A1 (0.50) TSHRALDH1A1
SCHEMBL28557645 0.81 TSHR (0.35) TSHRACHE
SCHEMBL4205109 0.81 THRB (0.32)
SCHEMBL15637 0.79 TSHR (0.43) TSHRACHEALDH1A1
SCHEMBL285423 0.79 TSHR (0.43) TSHRACHEALDH1A1
SCHEMBL28569697 0.79 TSHR (0.43) TSHRACHEALDH1A1
SCHEMBL5870616 0.77 TSHR (0.41) TSHRACHEALDH1A1
SCHEMBL9064397 0.77 TSHR (0.41) TSHRACHEALDH1A1
SCHEMBL23002362 0.75 TSHR (0.40) TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547369-B1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK-COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX UNIV KING SAUD (SA) 2017-04-19 EP claimed
EP-2547369-B1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK-COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX UNIV KING SAUD (SA) 2017-04-19 EP disclosed
EP-3041510-A1 POLYMER MICELLE CONTAINING A PHOTOSENSITIZER Wroclawskie Centrum Badan EIT + SP Z O.O. (PL) 2016-07-13 EP disclosed
WO-2015034381-A1 POLYMER MICELLE CONTAINING A PHOTOSENSITIZER WROCŁAWSKIE CENTRUM BADAŃ EIT+ SP. Z O.O. (PL) 2015-03-12 WO disclosed
EP-2547369-A1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK- COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX King Saud University (SA) 2013-01-23 EP disclosed
WO-2011113616-A9 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK- COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX KING SAUD UNIVERSITY (SA) 2011-11-17 WO disclosed
WO-2011113616-A1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK- COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX KING SAUD UNIVERSITY (SA) 2011-09-22 WO disclosed
US-7732546-B2 Use of silylated sulfonate monomers to improve contact lens wettability BAUSCH & LOMB INCORPORATED (US) 2010-06-08 US disclosed
US-20090093596-A1 USE OF SILYLATED SULFONATE MONOMERS TO IMPROVE CONTACT LENS WETTABILITY SOLTA MEDICAL IRELAND LIMITED (IE) 2009-04-09 US disclosed