Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381633 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL4642491 | 0.81 | HCAR2 (0.38) | THRB | |
| SCHEMBL19582862 | 0.78 | ALDH1A1 (0.50) | — | |
| SCHEMBL679847 | 0.75 | THRB (0.57) | THRB | |
| SCHEMBL11809058 | 0.73 | THRB (0.37) | THRB | |
| SCHEMBL1155519 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL7566089 | 0.71 | — | — | |
| SCHEMBL11806859 | 0.70 | THRB (0.61) | THRB | |
| SCHEMBL11805482 | 0.70 | THRB (0.61) | THRB | |
| SCHEMBL11806965 | 0.70 | THRB (0.61) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071704-B2 | Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups | BAUSCH & LOMB INCORPORATED (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090092655-A1 | NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) | 2009-04-09 | — | — | US | disclosed |
| WO-2009045886-A1 | NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092655-A1 | NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | NOTUM, ITK, MFAP1 | THRB 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.