Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEM1B | Q9UK73 | 2/20 | 0.55 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818554 | 0.94 | FEM1B (0.55) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817969 | 0.84 | FNIP1 (0.67) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23818422 | 0.81 | FEM1B (0.60) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23818425 | 0.81 | FEM1B (0.57) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30132893 | 0.79 | FEM1B (0.59) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23804984 | 0.79 | FEM1B (0.59) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817966 | 0.79 | FEM1B (0.61) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817837 | 0.78 | FEM1B (0.54) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23818490 | 0.76 | FNIP1 (0.53) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25455177 | 0.75 | FNIP1 (0.53) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |