Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 4/20 | 1.00 |
| ▸ | FLT3 | P36888 | 2/20 | 1.00 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.98 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.98 |
| ▸ | MYLK | Q15746 | 1/20 | 0.98 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 14/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 14/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29547897 | 1.00 | MELK (1.00) | MELKFLT3CAMK2GCAMK2DMYLK | |
| Hydrochloric Acid SCHEMBL30341843 | 0.99 | MELK (1.00) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20290866 | 0.87 | MELK (0.77) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20291161 | 0.85 | MELK (0.74) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20290500 | 0.85 | MELK (0.73) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20291125 | 0.85 | MELK (0.73) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20291298 | 0.83 | MELK (0.71) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20290838 | 0.82 | MELK (0.70) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20291160 | 0.82 | MELK (0.69) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL20290843 | 0.81 | MELK (0.67) | MELKFLT3CAMK2GCAMK2DMYLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283139-A1 | BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 | AMPHISTA THERAPEUTICS LIMITED (GB) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283139-A1 | BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 | UCHL5, UCHL3, UCHL1 | MELK 2124/4885FLT3 3129/4885CAMK2G 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.