Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26827134 | 0.88 | POLRMT (0.37) | POLRMT | |
| SCHEMBL26235740 | 0.85 | POLRMT (0.38) | POLRMT | |
| SCHEMBL23844096 | 0.82 | POLRMT (0.37) | POLRMT | |
| SCHEMBL25776813 | 0.80 | POLRMT (0.40) | POLRMT | |
| SCHEMBL23900278 | 0.75 | POLRMT (0.39) | POLRMTMAP4K4 | |
| SCHEMBL25244021 | 0.72 | POLRMT (0.36) | POLRMTPIK3CDMAP4K4 | |
| SCHEMBL19101840 | 0.72 | POLRMT (0.36) | POLRMTPIK3CDMAP4K4 | |
| SCHEMBL25077335 | 0.71 | POLRMT (0.38) | POLRMTMAP4K4 | |
| SCHEMBL13532207 | 0.70 | PI4KA (0.47) | POLRMTMAP4K4 | |
| SCHEMBL16710454 | 0.70 | PI4KA (0.47) | POLRMTMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295201-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20210284669-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295201-A1 | ANTIVIRAL COMPOUNDS | MAVS, HAVCR2, ZC3HAV1 | POLRMT 535/4885PIK3CD 4286/4885MAP4K4 1073/4885 |
| US-20210284669-A1 | ANTIVIRAL COMPOUNDS | MAVS, HAVCR2, SNRPA | POLRMT 352/4885PIK3CD 4304/4885MAP4K4 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.