Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23819043 | 1.00 | CTSL (0.38) | CTSLPDE4DGPR119MLNRABCB11 | |
| SCHEMBL31461598 | 1.00 | CTSL (0.38) | CTSLPDE4DGPR119MLNRABCB11 | |
| Hydrochloric Acid SCHEMBL30338425 | 0.98 | CTSL (0.38) | CTSLPDE4DGPR119MLNRABCB11 | |
| SCHEMBL720728 | 0.89 | L3MBTL1 (0.38) | LMNAACACBL3MBTL1PIK3CD | |
| SCHEMBL720729 | 0.89 | L3MBTL1 (0.38) | LMNAACACBL3MBTL1PIK3CD | |
| Hydrochloric Acid SCHEMBL17005254 | 0.87 | L3MBTL1 (0.37) | LMNAACACBL3MBTL1PIK3CD | |
| Hydrochloric Acid SCHEMBL17005253 | 0.87 | L3MBTL1 (0.37) | LMNAACACBL3MBTL1PIK3CD | |
| SCHEMBL30931383 | 0.86 | CTSL (0.37) | CTSLPDE4DGPR119MLNRABCB11 | |
| SCHEMBL8040912 | 0.85 | CTSL (0.40) | CTSLPDE4DGPR119ACACBPDE4A | |
| SCHEMBL8035844 | 0.85 | CTSL (0.40) | CTSLPDE4DGPR119ACACBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767337-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767337-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230295201-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230295201-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20210284670-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295201-A1 | ANTIVIRAL COMPOUNDS | MAVS, HAVCR2, ZC3HAV1 | CTSL 760/4885PDE4D 1783/4885GPR119 1269/4885 |
| US-20210284670-A1 | ANTIVIRAL COMPOUNDS | MAVS, HAVCR2, ZC3HAV1 | CTSL 760/4885PDE4D 1783/4885GPR119 1269/4885 |
| US-11767337-B2 | Antiviral compounds | MAVS, HAVCR2, ZC3HAV1 | CTSL 760/4885PDE4D 1783/4885GPR119 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.