Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522748 | 0.75 | KDM4E (0.39) | KDM4EKDM5CPHF8KDM2AHIF1A | |
| SCHEMBL14510738 | 0.73 | — | — | |
| SCHEMBL17011955 | 0.69 | — | — | |
| SCHEMBL7557631 | 0.69 | — | — | |
| SCHEMBL23566530 | 0.67 | CYP1A2 (0.36) | KDM4EKDM5CPHF8KDM2AHIF1A | |
| SCHEMBL17234465 | 0.67 | CYP1A2 (0.36) | KDM4EKDM5CPHF8KDM2AHIF1A | |
| Guanidino Acetate SCHEMBL33971 | 0.66 | — | — | |
| SCHEMBL7574469 | 0.65 | LDHA (0.40) | KDM4EHIF1ACPB1CYP1A2CYP2D6 | |
| SCHEMBL7574472 | 0.65 | LDHA (0.40) | KDM4EHIF1ACPB1CYP1A2CYP2D6 | |
| SCHEMBL18528405 | 0.64 | PHF8 (0.39) | KDM4EKDM5CPHF8KDM2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283574-A1 | Multivariate and other metal-organic frameworks, and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283574-A1 | Multivariate and other metal-organic frameworks, and uses thereof | AQP3, AQP4, AQP1 | KDM4E 4017/4885KDM5C 4377/4885PHF8 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.