Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202602 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP1A1CYP1B1ESR1AHR | |
| SCHEMBL23202604 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP1A1CYP1B1ESR1AHR | |
| SCHEMBL5647847 | 0.83 | KIF11 (0.41) | ALDH1A1CA1CA2CNR1CNR2 | |
| SCHEMBL20140282 | 0.83 | AHR (0.39) | ALDH1A1CYP1A1CYP1B1AHRPTGS2 | |
| SCHEMBL5647840 | 0.83 | KIF11 (0.41) | ALDH1A1CA1CA2CNR1CNR2 | |
| SCHEMBL20140283 | 0.83 | AHR (0.39) | ALDH1A1CYP1A1CYP1B1AHRPTGS2 | |
| SCHEMBL20156773 | 0.83 | AHR (0.39) | ALDH1A1CYP1A1CYP1B1AHRPTGS2 | |
| SCHEMBL23162444 | 0.80 | CNR1 (0.45) | AHRPOLBPTGS2CYP1A2CNR1 | |
| SCHEMBL23162443 | 0.80 | CNR1 (0.45) | AHRPOLBPTGS2CYP1A2CNR1 | |
| SCHEMBL23819513 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A1CYP1B1ESR1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284621-A1 | CANNABINOIDS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284621-A1 | CANNABINOIDS AND USES THEREOF | CNR2, CNR1, FAAH | ALDH1A1 2486/4885CYP1A1 964/4885CYP1B1 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.