Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 8/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.42 |
| ▸ | LDHB | P07195 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558948 | 0.84 | MEN1 (0.42) | DPP4AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL2787863 | 0.84 | DPP4 (0.57) | DPP4AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL23823369 | 0.84 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL691741 | 0.82 | AKR1C2 (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL27916176 | 0.82 | MEN1 (0.41) | DPP4AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL5318766 | 0.82 | AKR1C2 (0.61) | DPP4AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL8467731 | 0.80 | MYC (0.43) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL5961110 | 0.80 | AKR1C2 (0.59) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL10785106 | 0.80 | LDHA (0.48) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL27534718 | 0.80 | LDHA (0.44) | DPP4ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341379-B | Benzothiazine derivative, its preparation method and the application as medicine thereof | PIERRE FABRE MEDICAMENT (FR) | 2015-08-26 | — | — | CN | disclosed |