Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824820 | 0.81 | RAB9A (0.39) | MPOSLC6A4DPP4MAOBGAA | |
| SCHEMBL23824814 | 0.75 | DPP4 (0.40) | DPP4GAAHDAC4P2RX7AKT1 | |
| SCHEMBL17824476 | 0.75 | GAA (0.37) | MAOBGAAHDAC4P2RX7 | |
| SCHEMBL28488441 | 0.72 | GAA (0.37) | GAAHDAC4P2RX7 | |
| SCHEMBL28488443 | 0.72 | GAA (0.37) | GAAHDAC4P2RX7 | |
| SCHEMBL28485908 | 0.67 | GAA (0.35) | MAOBGAAHDAC4P2RX7 | |
| SCHEMBL2773140 | 0.67 | MAOB (0.57) | MPOMAOB | |
| SCHEMBL24791637 | 0.66 | ADRB2 (0.52) | — | |
| SCHEMBL30083519 | 0.66 | ADRB2 (0.52) | — | |
| SCHEMBL31500159 | 0.66 | MAPK1 (0.43) | HDAC4P2RX7AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230254-B1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND CONDITIONS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2021-09-22 | — | — | EP | disclosed |