Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824815 | 0.81 | MPO (0.41) | GAAMAOBMPOSLC6A4HDAC4 | |
| SCHEMBL19300673 | 0.71 | SLC6A4 (0.48) | MAOBMPOSLC6A4TAAR1CYP17A1 | |
| SCHEMBL23824819 | 0.71 | KDM4E (0.37) | RAB9ASMN1; SMN2HSD17B10KDM4EMEN1 | |
| SCHEMBL17824433 | 0.71 | ADRB2 (0.42) | RAB9ASMN1; SMN2HSD17B10KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL20742875 | 0.70 | MAOB (0.49) | KMT2AMAOBMPOSLC6A4TAAR1 | |
| SCHEMBL3387483 | 0.70 | FYN (0.44) | RAB9ASMN1; SMN2HSD17B10KDM4EMEN1 | |
| SCHEMBL16317115 | 0.70 | TP53 (0.46) | RAB9ASMN1; SMN2HSD17B10KDM4EMEN1 | |
| SCHEMBL3387425 | 0.70 | HDAC4 (0.38) | RAB9ASMN1; SMN2HSD17B10KDM4EMEN1 | |
| SCHEMBL3011039 | 0.70 | HDAC4 (0.41) | RAB9ASMN1; SMN2HSD17B10KDM4EMEN1 | |
| SCHEMBL9387012 | 0.68 | KDM4E (0.40) | KDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230254-B1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND CONDITIONS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2021-09-22 | — | — | EP | disclosed |