Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23825840 | 0.86 | KDM1A (0.46) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL23825838 | 0.86 | KDM1A (0.46) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL23827000 | 0.81 | KDM4E (0.56) | KMT2A | |
| SCHEMBL23826798 | 0.81 | CRHR1 (0.54) | DRD2KDM1AMAOBACACBACACA | |
| SCHEMBL23826796 | 0.81 | CRHR1 (0.54) | DRD2KDM1AMAOBACACBACACA | |
| SCHEMBL23826504 | 0.80 | KDM1A (0.41) | DRD2KDM1AMAOBCRHR1KMT2A | |
| SCHEMBL2392456 | 0.78 | DRD2 (0.45) | DRD2KDM1AMAOBDRD3CRHR1 | |
| SCHEMBL15342786 | 0.78 | DRD2 (0.45) | DRD2KDM1AMAOBDRD3CRHR1 | |
| SCHEMBL2392460 | 0.78 | DRD2 (0.45) | DRD2KDM1AMAOBDRD3CRHR1 | |
| SCHEMBL23826847 | 0.78 | PTGER4 (0.56) | DRD2KDM1AMAOBACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882239-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2021-09-22 | — | — | EP | disclosed |