Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | BTK | Q06187 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23825838 | 1.00 | KDM1A (0.46) | KDM1AMAOBHCAR3BTKKMT2A | |
| SCHEMBL29366142 | 0.88 | MAPK14 (0.42) | KDM1AMAOBBTKKMT2AL3MBTL1 | |
| SCHEMBL23825779 | 0.86 | DRD2 (0.42) | KDM1AMAOBKMT2AL3MBTL1DRD2 | |
| SCHEMBL23826085 | 0.86 | ALOX15 (0.49) | KDM1AMAOBBTKDRD2EPHX2 | |
| SCHEMBL23826087 | 0.86 | ALOX15 (0.49) | KDM1AMAOBBTKDRD2EPHX2 | |
| SCHEMBL23826504 | 0.85 | KDM1A (0.41) | KDM1AMAOBBTKKMT2AL3MBTL1 | |
| SCHEMBL2428995 | 0.83 | DRD2 (0.44) | KDM1AMAOBHCAR3BTKKMT2A | |
| SCHEMBL2428992 | 0.83 | DRD2 (0.44) | KDM1AMAOBHCAR3BTKKMT2A | |
| SCHEMBL31336610 | 0.77 | KDM1A (0.48) | KDM1AMAOBBTKKMT2AL3MBTL1 | |
| SCHEMBL25042395 | 0.76 | KDM1A (0.45) | KDM1AMAOBBTKKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3882239-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2021-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | PIM1, PIM3, PIM2 | KDM1A 334/4885MAOB 2103/4885HCAR3 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.