Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634533 | 0.90 | GBA2 (0.42) | GBA2 | |
| SCHEMBL15363092 | 0.86 | GBA1 (0.45) | SIGMAR1GBA2 | |
| SCHEMBL18501202 | 0.84 | GBA1 (0.39) | — | |
| SCHEMBL17194448 | 0.79 | GBA1 (0.45) | HRH3 | |
| SCHEMBL14767903 | 0.79 | SIGMAR1 (0.33) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL25530401 | 0.79 | SIGMAR1 (0.33) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL2559635 | 0.78 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL19144761 | 0.75 | S1PR1 (0.46) | SIGMAR1 | |
| SCHEMBL25597181 | 0.74 | NCF1 (0.41) | ACHE | |
| SCHEMBL17194447 | 0.72 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306008-B2 | Working medium and water treatment system | KABUSHIKI KAISHA TOSHIBA (JP) | 2022-04-19 | — | — | US | claimed |
| US-20210292194-A1 | WORKING MEDIUM AND WATER TREATMENT SYSTEM | KABUSHIKI KAISHA TOSHIBA (JP) | 2021-09-23 | — | — | US | claimed |
| US-11306008-B2 | Working medium and water treatment system | KABUSHIKI KAISHA TOSHIBA (JP) | 2022-04-19 | — | — | US | disclosed |
| US-20210292194-A1 | WORKING MEDIUM AND WATER TREATMENT SYSTEM | KABUSHIKI KAISHA TOSHIBA (JP) | 2021-09-23 | — | — | US | disclosed |