2,4-Diaminophenol

2,4-Diaminophenol

SCHEMBL2382912

Nc1ccc(O)c(N)c1.Nc1ccc(O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.62
HSD17B10 Q99714 6/20 0.62
ALOX15 P16050 5/20 0.62
HIF1A Q16665 3/20 0.62
CASP1 P29466 3/20 0.62
THRB P10828 3/20 0.62
CA14 Q9ULX7 2/20 0.62
CYP3A4 P08684 2/20 0.62
CA3 P07451 1/20 0.62
CA6 P23280 1/20 0.62
GAA P10253 5/20 0.48
ALOX12 P18054 3/20 0.48
HTT P42858 2/20 0.48
APP P05067 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
HPGD P15428 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MAPK1 P28482 1/20 0.48
PDE10A Q9Y233 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Diaminophenol SCHEMBL27284 0.90
2,4-Diaminophenol SCHEMBL11222476 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL30192203 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL28147894 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL7221197 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL456211 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL29389205 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL1884352 0.87 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX15HIF1ACASP1
4-Aminophenol SCHEMBL7705404 0.86 ALDH1A1 (0.61) ALDH1A1HSD17B10ALOX15HIF1ACASP1
2,4-Diaminophenol SCHEMBL7751374 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10ALOX15HIF1ACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453477-B1 DEVELOPER-COUPLER COMBINATION CONTAINING 2,4-DICHLORO-3-AMINOPHENOL HENKEL KGAA (DE) 2007-10-17 EP claimed
US-8012676-B2 Process for preparing conductive material MITSUBISHI PAPER MILLS LIMITED (JP) 2011-09-06 US disclosed
US-20090233237-A1 Process For Preparing Conductive Material MITSUBISHI PAPER MILLS LIMITED (JP) 2009-09-17 US disclosed
CN-101473386-A Method for producing conductive material MITSUBISHI PAPER MILLS LTD (JP) 2009-07-01 CN disclosed
US-4416980-A High-contrast light-sensitive silver halide photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-11-22 US disclosed