Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830004 | 1.00 | CHRNA7 (0.60) | CHRNA7ABCG2NR1H4BACE1TYR | |
| SCHEMBL17975272 | 0.90 | CHRNA7 (0.76) | CHRNA7ABCG2NR1H4BACE1TYR | |
| SCHEMBL4865615 | 0.84 | BCHE (0.56) | CHRNA7NR1H4NFE2L2KDM4EMEN1 | |
| SCHEMBL29018468 | 0.83 | MAPT (0.67) | CHRNA7ABCG2TYRCAPN1CTSL | |
| SCHEMBL9629524 | 0.81 | MEN1 (0.48) | CHRNA7ABCG2NR1H4KDM4EMEN1 | |
| SCHEMBL9629519 | 0.81 | MEN1 (0.48) | CHRNA7ABCG2NR1H4KDM4EMEN1 | |
| SCHEMBL31398696 | 0.81 | CHRNA7 (0.76) | CHRNA7ABCG2NR1H4BACE1TYR | |
| SCHEMBL31398711 | 0.81 | CHRNA7 (0.76) | CHRNA7ABCG2NR1H4BACE1TYR | |
| SCHEMBL675698 | 0.80 | BCHE (0.75) | CHRNA7KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8101054 | 0.80 | BCHE (0.75) | CHRNA7KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292265-A1 | CHALCONES AND DERIVATIVES FOR USE IN MEDICAMENTS AND NUTRACEUTICALS | HLXTH B.V. (NL) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292265-A1 | CHALCONES AND DERIVATIVES FOR USE IN MEDICAMENTS AND NUTRACEUTICALS | IL1B, IL1A, IL1R1 | CHRNA7 3383/4885ABCG2 4093/4885NR1H4 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.