Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL23830443

Fc1ccc(CC2CNC2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.61
SLC6A4 P31645 3/20 0.61
SLC6A3 Q01959 3/20 0.61
GRM2 Q14416 1/20 0.42
GRM3 Q14832 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TRPA1 O75762 1/20 0.40
CPA1 P15085 1/20 0.40
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL17542042 0.87 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
Trifluoroacetic Acid SCHEMBL5224978 0.86 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
Trifluoroacetic Acid SCHEMBL30548820 0.86 SLC6A4 (0.47) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
SCHEMBL17296085 0.85 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3TRPA1
Hydrochloric Acid SCHEMBL17296112 0.83 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL18497346 0.77 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4
Trifluoroacetic Acid SCHEMBL18863016 0.77 EPHX2 (0.54) MEN1KMT2A
SCHEMBL15166135 0.75 GRIK1 (0.52) MEN1KMT2A
Trifluoroacetic Acid SCHEMBL19994597 0.75 ITGB3 (0.50) SLC6A2SLC6A4SLC6A3GRM2GRM3
Bicarbonate SCHEMBL9362828 0.74 EPHX2 (0.52) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210292305-A1 Cyclic Ureas SIRONAX LTD (KY) 2021-09-23 US disclosed
CN-113302183-A Cyclic ureas 圣瑞诺有限公司 2021-08-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292305-A1 Cyclic Ureas RIPK1, RIPK3, RIPK4 SLC6A2 4844/4885SLC6A4 4608/4885SLC6A3 4703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.