Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 15/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830554 | 1.00 | RIPK1 (0.47) | RIPK1LMNAHTR2AHTR2CFAAH | |
| SCHEMBL20168830 | 0.88 | RIPK1 (0.58) | RIPK1 | |
| SCHEMBL20168833 | 0.88 | RIPK1 (0.58) | RIPK1 | |
| SCHEMBL23831076 | 0.87 | RIPK1 (0.48) | RIPK1FAAH | |
| SCHEMBL23831078 | 0.87 | RIPK1 (0.48) | RIPK1FAAH | |
| SCHEMBL23830891 | 0.85 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL24055256 | 0.83 | RIPK1 (0.47) | RIPK1LMNA | |
| SCHEMBL25281525 | 0.83 | RIPK1 (0.47) | RIPK1LMNA | |
| SCHEMBL25279629 | 0.82 | RIPK1 (0.46) | RIPK1LMNA | |
| SCHEMBL24055501 | 0.82 | RIPK1 (0.46) | RIPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | RIPK1 1/4885LMNA 3380/4885HTR2A 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.