Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601052 | 0.86 | CYP3A4 (0.38) | L3MBTL1CYP3A4TRPV1MAPK1ALDH1A1 | |
| SCHEMBL23830940 | 0.86 | CYP3A4 (0.38) | L3MBTL1CYP3A4TRPV1MAPK1ALDH1A1 | |
| SCHEMBL23830616 | 0.85 | CYP3A4 (0.38) | L3MBTL1CYP3A4TRPV1MAPK1ALDH1A1 | |
| SCHEMBL23830618 | 0.85 | CYP3A4 (0.38) | L3MBTL1CYP3A4TRPV1MAPK1ALDH1A1 | |
| SCHEMBL18601016 | 0.82 | USP2 (0.48) | L3MBTL1CYP3A4TRPV1ALDH1A1GAA | |
| SCHEMBL18601015 | 0.82 | USP2 (0.48) | L3MBTL1CYP3A4TRPV1ALDH1A1GAA | |
| SCHEMBL28613955 | 0.82 | USP2 (0.48) | L3MBTL1CYP3A4TRPV1ALDH1A1GAA | |
| SCHEMBL18209180 | 0.78 | L3MBTL1 (0.63) | L3MBTL1CYP3A4TRPV1MAPK1ALDH1A1 | |
| SCHEMBL17055837 | 0.78 | L3MBTL1 (0.63) | L3MBTL1CYP3A4TRPV1MAPK1ALDH1A1 | |
| SCHEMBL7476434 | 0.78 | L3MBTL1 (0.63) | L3MBTL1CYP3A4TRPV1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | L3MBTL1 3909/4885CYP3A4 4028/4885TRPV1 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.