Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | NRAS | P01111 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.42 |
| ▸ | PRKCI | P41743 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830884 | 1.00 | CTSK (0.66) | CTSKHRH3HRH4NRASFLT3 | |
| SCHEMBL27226580 | 0.92 | CTSK (0.74) | CTSKHRH3HRH4IRAK4CYP1A2 | |
| SCHEMBL30815053 | 0.92 | CTSK (0.74) | CTSKHRH3HRH4IRAK4CYP1A2 | |
| SCHEMBL27226113 | 0.88 | CTSK (0.68) | CTSKHRH3HRH4NRASFLT3 | |
| SCHEMBL31627243 | 0.82 | CTSK (0.53) | CTSKHRH3HRH4CYP1A2CYP2C19 | |
| SCHEMBL30815368 | 0.81 | CTSK (0.58) | CTSKHRH3HRH4IRAK4CYP1A2 | |
| SCHEMBL31061062 | 0.80 | CTSK (1.00) | CTSKHRH3CTSLCTSBCTSS | |
| SCHEMBL13018653 | 0.78 | HRH3 (0.83) | HRH3HRH4NRASFLT3IRAK4 | |
| SCHEMBL3785005 | 0.78 | HRH3 (0.83) | HRH3HRH4NRASFLT3IRAK4 | |
| SCHEMBL30815456 | 0.78 | CTSK (0.62) | CTSKHRH3HRH4FLT3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| US-20210292305-A1 | Cyclic Ureas | SIRONAX LTD (KY) | 2021-09-23 | — | — | US | disclosed |
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292305-A1 | Cyclic Ureas | RIPK1, RIPK3, RIPK4 | CTSK 2802/4885HRH3 1156/4885HRH4 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.