SCHEMBL238312

SCHEMBL238312

[CH2]CCC(C)CCCC(C)CCCC(C)C

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.68
BLM P54132 1/20 0.48
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN1 P18031 3/20 0.42
PTPN2 P17706 1/20 0.32
CDC25B P30305 1/20 0.32
FNTA P49354 1/20 0.31
PGGT1B P53609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1193294 1.00 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL386229 1.00 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL632397 0.94 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL3337422 0.89 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL7269036 0.86 LMNA (0.74) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL10945252 0.86 LMNA (0.74) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL10991364 0.85 LMNA (0.53) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL20928 0.85 LMNA (0.93) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL538230 0.85 LMNA (0.93) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL8672325 0.85 LMNA (0.93) LMNABLMMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322695-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY 2023-10-12 US claimed
WO-2023147531-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2023-08-03 WO claimed
CN-110268066-B Enzymatic reaction medium containing surfactant 诺华股份有限公司 2023-07-07 CN claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2018134710-A1 ENZYMATIC REACTION MEDIUM CONTAINING SURFACTANT NOVARTIS AG (CH) 2018-07-26 WO claimed
CN-103732676-B What have excellence is the polyolefin compositions for tubing of color stability and thermostability and scale resistance 北欧化工股份公司 2016-06-15 CN claimed
EP-2551297-B1 Polyolefin composition with excellent colour and thermal stability as well as oxidation resistance for pipes BOREALIS AG (AT) 2014-03-12 EP claimed
WO-2013013805-A1 POLYOLEFIN COMPOSITION WITH EXCELLENT COLOUR AND THERMAL STABILITY AS WELL AS OXIDATION RESISTANCE FOR PIPES BOREALIS AG (AT) 2013-01-31 WO claimed
EP-2551297-A1 Polyolefin composition with excellent colour and thermal stability as well as oxidation resistance for pipes Borealis AG (AT) 2013-01-30 EP claimed
CN-101680124-B High tenacity polyethylene yarn HONEYWELL INT INC 2012-09-05 CN claimed
CN-101680124-A High tenacity polyethylene yarn HONEYWELL INT INC 2010-03-24 CN claimed
EP-1013652-B1 Process for preparation of substituted chromanderivatives BASF AG (DE) 2002-08-14 EP claimed
JP-2001526219-A 2001-12-18 JP claimed
US-6136985-A COMPRISING CONJUGATED LINOLEIC ACID ESTERS SUCH AS TOCOPHERYL ESTER, ASCORBYL ESTERS; IN COSMETICS FOR TOPICAL USE; INHIBITS EPIDERMAL CARCINOGENESIS DCV, INC. (US) 2000-10-24 US claimed
EP-1041979-A1 ESTERS OF CONJUGATED LINOLEIC ACID OR CONJUGATED LINOLENIC ACID AND USES THEREOF DCV Inc. doing business as Bio-Technical Resourses (US) 2000-10-11 EP claimed
EP-1013652-A2 Process for preparation of substituted chromanderivatives BASF AKTIENGESELLSCHAFT (DE) 2000-06-28 EP claimed
EP-0188079-B1 USE OF TOCOPHERYL GLYCOSIDES FOR ACTIVATING THE FUNCTION OF PHAGOCYTES DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-04-08 EP claimed
EP-0169716-B1 PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING ANTIALLERGIC ACTIVITY DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-10-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB LMNA 344/4885BLM 1854/4885MEN1 1711/4885
US-20230322695-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE PTPN2, PTPN22, PTPN5 LMNA 4590/4885BLM 2909/4885MEN1 3883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.