SCHEMBL386229

SCHEMBL386229

[CH2]CCC(C)CCCC(C)C

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.68
BLM P54132 1/20 0.48
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN1 P18031 3/20 0.42
PTPN2 P17706 1/20 0.32
CDC25B P30305 1/20 0.32
FNTA P49354 1/20 0.31
PGGT1B P53609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238312 1.00 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL1193294 1.00 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL632397 0.94 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL3337422 0.89 LMNA (0.68) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL7269036 0.86 LMNA (0.74) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL10945252 0.86 LMNA (0.74) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL10991364 0.85 LMNA (0.53) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL20928 0.85 LMNA (0.93) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL538230 0.85 LMNA (0.93) LMNABLMMEN1CYP3A4ALOX15
SCHEMBL8672325 0.85 LMNA (0.93) LMNABLMMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021086689-A1 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF PRIME REACH TRADING LIMITED (WS) 2021-05-06 WO claimed
US-20150141502-A1 INHIBITION OF LEUKEMIC STEM CELLS BY PP2A ACTIVATING AGENTS Ohio State Innvation Foundation (US) 2015-05-21 US claimed
WO-2013181488-A2 INHIBITION OF LEUKEMIC STEM CELLS BY PP2A ACTIVATING AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2013-12-05 WO claimed
EP-2418948-B1 ANTIADHESION AGENTS UNIV OHIO STATE RES FOUND (US) 2013-09-04 EP claimed
EP-2419414-A1 PROTEIN PHOSPHATASE 2A-ACTIVATING AGENTS The Ohio State University Research Foundation (US) 2012-02-22 EP claimed
EP-2418948-A1 ANTIADHESION AGENTS The Ohio State University Research Foundation (US) 2012-02-22 EP claimed
WO-2010121111-A9 ANTIADHESION AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-12-22 WO claimed
US-20100267673-A1 PROTEIN PHOSPHATASE 2A-ACTIVATING AGENTS THE OHIO SATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-10-21 US claimed
US-20100267820-A1 ANTIADHESION AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-10-21 US claimed
WO-2010121111-A1 ANTIADHESION AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-10-21 WO claimed
WO-2010120711-A1 PROTEIN PHOSPHATASE 2A-ACTIVATING AGENTS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-10-21 WO claimed
US-4115466-A ACETYLENIC HYDROCARBONS FROM ACETYLENIC CARBINOLS, ISOMERIZATION SCM CORPORATION (US) 1978-09-19 US claimed
US-3975446-A FROM UNSATURATED ALCOHOL, TERTIARY AMINE SHINETSU CHEMICAL COMPANY (JA) 1976-08-17 US claimed
EP-3837247-B1 SYNTHESIS OF CHROMANOL DERIVATIVES BASF SE (DE) 2024-06-05 EP disclosed
CN-110325646-B Process for preparing (3E, 7E) -Gao Fani acid or (3E, 7E) -Gao Fani acid esters 巴斯夫欧洲公司 2024-02-09 CN disclosed
WO-2023238837-A1 EXOSOME COMPLEX AND MANUFACTURING METHOD THEREOF JSR株式会社 2023-12-14 WO disclosed
US-4073813-A PLATINUM REDUCTION CATALYST, ALDEHYDES, HYDROGEN RHONE-POULENC INDUSTRIES (FR) 1978-02-14 US disclosed
US-4055575-A HYDROGENATION, SAPONIFICATION SCM CORPORATION (US) 1977-10-25 US disclosed
US-4039591-A 1-ACETOXY-4-CHLORO-3-METHYLBUT-2-ENE SCM CORPORATION (US) 1977-08-02 US disclosed
US-3975446-A FROM UNSATURATED ALCOHOL, TERTIARY AMINE SHINETSU CHEMICAL COMPANY (JA) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267673-A1 PROTEIN PHOSPHATASE 2A-ACTIVATING AGENTS PPP2CA, PPP2R2A, PPP2R1A LMNA 3602/4885BLM 4530/4885MEN1 4219/4885
US-20150141502-A1 INHIBITION OF LEUKEMIC STEM CELLS BY PP2A ACTIVATING AGENTS PPM1A, PPM1G, PPM1F LMNA 3971/4885BLM 4068/4885MEN1 1662/4885
US-20100267820-A1 ANTIADHESION AGENTS SELE, EPCAM, SELP LMNA 2725/4885BLM 3727/4885MEN1 1770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.