Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711927 | 0.85 | GPR35 (0.57) | MAPK1ALDH1A1CYP1A2AKR1B1HPGD | |
| SCHEMBL2711921 | 0.85 | GPR35 (0.57) | MAPK1ALDH1A1CYP1A2AKR1B1HPGD | |
| SCHEMBL5191843 | 0.81 | AKR1B1 (0.61) | FBP1TSHRALDH1A1AKR1B1CYP3A4 | |
| SCHEMBL47847 | 0.81 | TSHR (0.41) | FBP1TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL47848 | 0.81 | TSHR (0.41) | FBP1TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL30105031 | 0.81 | MEN1 (0.42) | MAPK1ALDH1A1VCAM1HPGDPOLB | |
| SCHEMBL47846 | 0.80 | TSHR (0.43) | FBP1TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL7643608 | 0.79 | TSHR (0.46) | FBP1TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL1407953 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CYP1A2AKR1B1VCAM1CYP3A4 | |
| SCHEMBL7311048 | 0.77 | FBP1 (0.44) | FBP1TSHRMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021185391-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-09-23 | — | — | WO | disclosed |