Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26128691 | 0.82 | FTO (0.57) | FTOPDE10AMAPTEGFRESR1 | |
| SCHEMBL716117 | 0.78 | TSHR (0.50) | TSHREGFR | |
| Hydrochloric Acid SCHEMBL27476977 | 0.76 | TSHR (0.49) | TSHREGFR | |
| SCHEMBL21865295 | 0.74 | MIF (0.41) | MIFBRAFCBFBPDE3BPDE3A | |
| SCHEMBL3716812 | 0.73 | LTA4H (0.55) | MIFFTOMAPTESR1ESR2 | |
| SCHEMBL21864851 | 0.73 | PIK3CD (0.40) | MIFPDE10AMAPTTSHREGFR | |
| SCHEMBL21864993 | 0.73 | AOC2 (0.51) | — | |
| SCHEMBL31731092 | 0.70 | MAPT (0.43) | FTOPDE10AMAPTESR1ESR2 | |
| SCHEMBL3962548 | 0.69 | FTO (0.57) | FTOEGFRESR1ESR2 | |
| SCHEMBL22101294 | 0.68 | ACACB (0.42) | BRAFMAPTPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121526-A1 | SYSTEMS AND METHODS TO TRACK THE EVOLUTION OF SINGLE CELLS | GENENTECH, INC. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188973-A1 | SYSTEMS AND METHODS TO TRACK THE EVOLUTION OF SINGLE CELLS | GENENTECH, INC. (US) | 2021-09-23 | — | — | WO | disclosed |