SCHEMBL23833684

SCHEMBL23833684

CC(C)(C)C#CCCCCl

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11719036 0.83
SCHEMBL3227769 0.80 LMNA (0.38) LMNA
Hydrochloric Acid SCHEMBL1359839 0.78 LMNA (0.37) LMNA
SCHEMBL1454301 0.74 LMNA (0.41) LMNA
SCHEMBL9254617 0.74 LMNA (0.41) LMNAALDH1A1
SCHEMBL31295860 0.74 LMNA (0.41) LMNATSHR
SCHEMBL312547 0.74 LMNA (0.41) LMNA
SCHEMBL9504251 0.74 LMNA (0.41) LMNA
SCHEMBL11673918 0.73 TSHR (0.46) TSHRTDP1ALDH1A1
SCHEMBL13918965 0.72 LMNA (0.44) LMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335358-B Synthesis of Capsaicin Derivatives 阿克西赫姆公司 2024-07-12 CN disclosed
US-11891351-B2 Synthesis of capsaicin derivatives AXICHEM AS (NO) 2024-02-06 US disclosed
US-20230060251-A1 SYNTHESIS OF CAPSAICIN DERIVATIVES AXICHEM AS (NO) 2023-03-02 US disclosed
EP-4121408-A1 SYNTHESIS OF CAPSAICIN DERIVATIVES Axichem AB (NO) 2023-01-25 EP disclosed
CN-115335358-A Synthesis of capsaicin derivatives 阿克西赫姆公司 2022-11-11 CN disclosed
WO-2021187992-A1 SYNTHESIS OF CAPSAICIN DERIVATIVES AXICHEM AS (NO) 2021-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891351-B2 Synthesis of capsaicin derivatives TRPV1, TRPV6, HCAR3 LMNA 4135/4885TSHR 4786/4885TDP1 4355/4885
US-20230060251-A1 SYNTHESIS OF CAPSAICIN DERIVATIVES TRPV1, TRPV6, HCAR3 LMNA 4135/4885TSHR 4786/4885TDP1 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.